The progressive intercontinental spread of methicillin-resistant Staphylococcus aureus.

@article{Ayliffe1997ThePI,
  title={The progressive intercontinental spread of methicillin-resistant Staphylococcus aureus.},
  author={Graham Ayliffe},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={1997},
  volume={24 Suppl 1},
  pages={S74-9}
}
  • Graham Ayliffe
  • Published 1997 in
    Clinical infectious diseases : an official…
Methicillin-resistant Staphylococcus aureus was initially detected in Europe in the 1960s, soon after the introduction of methicillin. Naturally-resistant strains were isolated in some countries before the use of methicillin or related agents. These strains probably spread initially from one or more ancestral genetic clones in natural populations of S. aureus by horizontal transfer and recombination. These original strains, possibly emerging in many countries, then increased in numbers and… CONTINUE READING