The progression of comorbidity in IL-18 transgenic chronic obstructive pulmonary disease mice model.


Patients with severe COPD are known to have comorbidities such as emaciation, cor pulmonale and right heart failure, muscle weakness, hyperlipemia, diabetes mellitus, osteoporosis, muscle atrophy, arterial sclerosis, hypertension, and depression. Therefore, treatment for COPD needs to focus on these comorbidities as well as the lungs. We previously reported… (More)
DOI: 10.1016/j.bbrc.2014.02.052


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