The progression of calcific aortic valve disease through injury, cell dysfunction, and disruptive biologic and physical force feedback loops.

Abstract

Calcific aortic valve disease (CAVD) is the most common form of heart valve disease in Western society and results in the second most common cardiovascular surgery performed. Despite its prevalence, high morbidity, and high mortality, the pathogenesis of CAVD still eludes our understanding. This review article brings together experimental in vivo and in… (More)
DOI: 10.1016/j.carpath.2012.06.005

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Cite this paper

@article{Li2013ThePO, title={The progression of calcific aortic valve disease through injury, cell dysfunction, and disruptive biologic and physical force feedback loops.}, author={Chen Li and Songyi Xu and Avrum I. Gotlieb}, journal={Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology}, year={2013}, volume={22 1}, pages={1-8} }