The prognostic value of measures of acid/base balance in pediatric falciparum malaria, compared with other clinical and laboratory parameters.

@article{Newton2005ThePV,
  title={The prognostic value of measures of acid/base balance in pediatric falciparum malaria, compared with other clinical and laboratory parameters.},
  author={Charles R Newton and Clarissa Valim and Sanjeev Krishna and David Wypij and Christopher H. O. Olola and Tsiri E Agbenyega and Terrie E. Taylor},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2005},
  volume={41 7},
  pages={948-57}
}
BACKGROUND Identifying severe, life-threatening falciparum malaria in African children allows for the prompt institution of appropriate management. In the past 2 decades, hyperlactatemia and acidosis have been identified as being associated with mortality in patients with severe malaria, but measurement of blood lactate concentration and base excess is expensive and technically demanding. In this large, prospective study, we examined the prognostic value of acidosis and hyperlactatemia and… CONTINUE READING

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