The prognostic value of TRAIL and its death receptors in cervical cancer.

@article{Maduro2009ThePV,
  title={The prognostic value of TRAIL and its death receptors in cervical cancer.},
  author={John H. Maduro and Maartje G. Noordhuis and Klaske A ten Hoor and Elisabeth Pras and Henriette J. G. Arts and Jasper J. H. Eijsink and Harry Hollema and Constantijne H Mom and Steven de Jong and Elisabeth G E de Vries and Geertruida H de Bock and Ate G J van der Zee},
  journal={International journal of radiation oncology, biology, physics},
  year={2009},
  volume={75 1},
  pages={
          203-11
        }
}
  • John H. Maduro, Maartje G. Noordhuis, +9 authors Ate G J van der Zee
  • Published in
    International journal of…
    2009
  • Medicine
  • PURPOSE Preclinical data indicate a synergistic effect on apoptosis between irradiation and recombinant human (rh) tumor necrosis factor-related apoptosis inducing ligand (TRAIL), making the TRAIL death receptors (DR) interesting drug targets. The aim of our study was to analyze the expression of DR4, DR5, and TRAIL in cervical cancer and to determine their predictive and prognostic value. METHODS AND MATERIALS Tissue microarrays were constructed from tumors of 645 cervical cancer patients… CONTINUE READING

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