The prognostic value of TRAIL and its death receptors in cervical cancer.

@article{Maduro2009ThePV,
  title={The prognostic value of TRAIL and its death receptors in cervical cancer.},
  author={J. Maduro and M. Noordhuis and K. T. ten Hoor and E. Pras and H. Arts and J. Eijsink and H. Hollema and C. Mom and S. de Jong and E. D. de Vries and G. D. de Bock and A. V. D. Van Der Zee},
  journal={International journal of radiation oncology, biology, physics},
  year={2009},
  volume={75 1},
  pages={
          203-11
        }
}
PURPOSE Preclinical data indicate a synergistic effect on apoptosis between irradiation and recombinant human (rh) tumor necrosis factor-related apoptosis inducing ligand (TRAIL), making the TRAIL death receptors (DR) interesting drug targets. The aim of our study was to analyze the expression of DR4, DR5, and TRAIL in cervical cancer and to determine their predictive and prognostic value. METHODS AND MATERIALS Tissue microarrays were constructed from tumors of 645 cervical cancer patients… Expand
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