The prognostic value of KRAS mutations in patients with colorectal cancer.

@article{Inoue2012ThePV,
  title={The prognostic value of KRAS mutations in patients with colorectal cancer.},
  author={Yasuhiro Inoue and Susumu Saigusa and T Hisato Iwata and Yoshinaga Okugawa and Yuji Toiyama and Koji Tanaka and Keiichi Uchida and Yasuhiko Mohri and Masato Kusunoki},
  journal={Oncology reports},
  year={2012},
  volume={28 5},
  pages={1579-84}
}
Our aim was to evaluate the KRAS genotypes of Japanese colorectal cancer (CRC) patients and to assess the effect of these genotypes on clinical outcome. A total of 99 patients with stage I-IV CRC who underwent resection were prospectively studied for KRAS mutations by direct sequencing. KRAS mutations were found in 37 (37.4%) of 99 patients. Of these, 11.1… CONTINUE READING

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