The prognostic value of E-cadherin in gastric cancer: a meta-analysis.

  title={The prognostic value of E-cadherin in gastric cancer: a meta-analysis.},
  author={Xiangbin Xing and Yong-Bo Tang and G. X.-Z. Yuan and Yongfei Wang and Jinhui Wang and Yang Yang and Minhu Chen},
  journal={International journal of cancer},
  volume={132 11},
The prognostic impact of E-cadherin downregulation in gastric cancer has been assessed for years while the results are controversial and heterogeneous. We thus comprehensively reviewed the evidence for evaluation of E-cadherin expression in gastric cancer to determine this effect. We searched PubMed and Embase to identify eligible studies, and 26 studies comprising 4,383 gastric cancer patients were included to assess the association between E-cadherin immunohistochemical expression and overall… CONTINUE READING


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