The prognostic value of E-cadherin, alpha-, beta-, and gamma-catenin in urothelial cancer of the upper urinary tract.

@article{Kashibuchi2006ThePV,
  title={The prognostic value of E-cadherin, alpha-, beta-, and gamma-catenin in urothelial cancer of the upper urinary tract.},
  author={Keishi Kashibuchi and Kyoichi Tomita and Jack A Schalken and Haruki Kume and Takuhiro Yamaguchi and Satoru Muto and Sigeo Horie and Tadaichi Kitamura},
  journal={European urology},
  year={2006},
  volume={49 5},
  pages={839-45; discussion 845}
}
OBJECTIVES To determine the value of loss of the expression of E-cadherin and cadherin-associated molecules as useful markers for both prognosis and bladder recurrence in patients with upper urinary tract cancer. MATERIALS AND METHODS In 61 paraffin-embedded nephroureterectomy specimens, the expression of E-cadherin and alpha-, beta-, and gamma-catenin was examined by immunohistochemical staining. To evaluate the prognostic significance, Kaplan-Meier survival curves were calculated and… CONTINUE READING

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