The prognostic significance of perineural invasion in prostatic cancer biopsies: a systematic review.

@article{Harnden2007ThePS,
  title={The prognostic significance of perineural invasion in prostatic cancer biopsies: a systematic review.},
  author={Patricia M Harnden and Michael D Shelley and Hayley Clements and Bernadette Coles and R Sandy Tyndale-Biscoe and B. P. Naylor and Malcolm David Mason},
  journal={Cancer},
  year={2007},
  volume={109 1},
  pages={13-24}
}
Men with clinically localized prostate cancer are faced with a wide range of treatment options, and only Gleason grading is universally used as a histopathological prognostic factor for this disease. The significance of perineural invasion in diagnostic biopsies is controversial. Opinion about whether or not it should influence treatment decisions is currently almost equally divided. To address this, the authors performed a systematic review of studies that examine the association between… CONTINUE READING