The prognostic significance of p53 and bcl-2 expression in lung adenocarcinoma and its correlation with Ki-67 growth fraction.

@article{Ishida1997ThePS,
  title={The prognostic significance of p53 and bcl-2 expression in lung adenocarcinoma and its correlation with Ki-67 growth fraction.},
  author={Haku Ishida and Koji Irie and Tomoo Itoh and Taiji Furukawa and O. Tokunaga},
  journal={Cancer},
  year={1997},
  volume={80 6},
  pages={1034-45}
}
BACKGROUND The p53 and bcl-2 gene deregulations are frequently involved in several types of epithelial malignancy. The aims of this study were to determine the relationships between the Ki-67 labeling index (LI) and the expression of p53 and bcl-2 protein in lung adenocarcinoma and to investigate the clinicopathologic features of the tumors and the prognostic significance of p53 and bcl-2. METHODS Immunohistochemical staining for p53, bcl-2, and Ki-67 was performed on paraffin embedded… CONTINUE READING
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