The prognostic significance of multiple morphologic features and biologic markers in ductal carcinoma in situ of the breast: a study of a large cohort of patients treated with surgery alone.

@article{Cornfield2004ThePS,
  title={The prognostic significance of multiple morphologic features and biologic markers in ductal carcinoma in situ of the breast: a study of a large cohort of patients treated with surgery alone.},
  author={Dennis B Cornfield and Juan Pablo Palazzo and Gordon Francis Schwartz and Shanth A Goonewardene and Albert J. Kovatich and Inna Chervoneva and Terry Hyslop and Roland S Schwarting},
  journal={Cancer},
  year={2004},
  volume={100 11},
  pages={2317-27}
}
BACKGROUND A number of conventional histopathologic features have been associated with recurrence of ductal carcinoma in situ (DCIS) after surgery alone and are included in the Van Nuys Pathologic Classification and Prognostic Index. To the authors' knowledge, very little is known regarding the prognostic significance of the many biologic markers that have been studied in DCIS in the past decade. METHODS Clinical and pathologic data were analyzed from 151 patients who underwent wide local… CONTINUE READING

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