The prognostic significance of MIB-1, p53, and DNA flow cytometry in completely resected primary meningiomas.

@article{Perry1998ThePS,
  title={The prognostic significance of MIB-1, p53, and DNA flow cytometry in completely resected primary meningiomas.},
  author={Archie C Perry and Scott L. Stafford and Bernd Walter Scheithauer and Vera J. Suman and Christine Marie Lohse},
  journal={Cancer},
  year={1998},
  volume={82 11},
  pages={2262-9}
}
BACKGROUND Despite the availability of clinical and pathologic parameters of prognosis, the behavior of an individual meningioma may be difficult to predict. In a recent review of gross totally resected (GTR) meningiomas, the authors found strong associations between microscopic brain invasion, increased mitotic rate (> or = 4/10 high-power fields), the presence of at least 3 of 4 morphologic variables (sheeting, hypercellularity, macronucleoli, and small cells), and decreased recurrence free… CONTINUE READING

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