The prognostic role of tumor-infiltrating CD4 and CD8 T lymphocytes in breast cancer.

@article{Matkowski2009ThePR,
  title={The prognostic role of tumor-infiltrating CD4 and CD8 T lymphocytes in breast cancer.},
  author={Rafal A Matkowski and Iwona J Gisterek and Agnieszka Haloń and Aleksandra Lacko and Krzysztof Szewczyk and Urszula Staszek and Marek Pudelko and Bartlomiej Szynglarewicz and Jolanta K Szelachowska and Andrzej Zolnierek and Jan A Kornafel},
  journal={Anticancer research},
  year={2009},
  volume={29 7},
  pages={2445-51}
}
BACKGROUND The aim of the study was to assess the prognostic role of CD4 and CD8 expression and the type, density, localization and distribution of tumor infiltrating lymphocytes (TILs) in patients with breast cancer. MATERIALS AND METHODS Tissue samples were obtained from 88 breast cancer patients with operable disease and ductal histology. Forty-three women had pathologically confirmed axillary lymph node involvement. The TILs and expression of CD8 (cytotoxic T-cells) and CD4 (T-helper… CONTINUE READING
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