The prognostic relevance of fascin expression in human gastric carcinoma.

Abstract

OBJECTIVE Fascin, an actin-bundling protein that is found in membrane ruffles, microspikes, and stress fibers, induces membrane protrusions and increases cell motility in various transformed cells. The expression of fascin in epithelial neoplasms has been described only recently, and its role in gastric cancer is still unknown. METHODS Paraffin sections… (More)

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