The Prognostic Impact of Soluble Apoptosis-Stimulating Fragment on Mortality in Patients With Carotid Atherosclerosis
@article{Hoke2011ThePI, title={The Prognostic Impact of Soluble Apoptosis-Stimulating Fragment on Mortality in Patients With Carotid Atherosclerosis}, author={Matthias Hoke and Martin Schillinger and Gerlinde Zorn and Anna Wonnerth and Jasmin Amighi and Wolfgang Mlekusch and Walter S. Speidl and Gerald Maurer and Renate Koppensteiner and Erich Minar and Johann Wojta and Alexander Niessner}, journal={Stroke}, year={2011}, volume={42}, pages={2465–2470}, url={https://api.semanticscholar.org/CorpusID:5827829} }
Markers of apoptosis, as measured by sFAS, were found to be independent risk predictors for death in patients with atherosclerotic disease in the carotid arteries.
8 Citations
Inflammation and apoptosis in hypertension. Relevance of the extent of target organ damage.
- 2012
Medicine
The role of immunity and inflammation in the development of diabetic complications
- 2013
Medicine
The human humoral autoimmune response to modified forms of LDL is a typical adaptive response, with a switch to IgG synthesis and increasing antibody affinity that leads to the release of proinflammatory mediators, and it has unquestionable pathogenic characteristics.
Soluble Fas ligand is associated with natural killer cell dynamics in coronary artery disease.
- 2014
Medicine
O R I G I N a L I N V E S T I G a T I O N Open Access
Medicine
Novel association of the obesity risk-allele near Fas Apoptotic Inhibitory Molecule 2 (FAIM2) gene with heart rate and study of its effects on myocardial infarction in diabetic participants of the…
Antibodies to Multiple Receptors are Associated with Neuropsychiatric Symptoms and Mortality in Alzheimer's Disease: A Longitudinal Study.
- 2018
Medicine
The associations between Abs, mortality, and neuropsychiatric symptoms reported in this cohort are intriguing, but they cannot, however, be generalized.
Detection of apoptosis in patients with coronary artery disease Assessment of temporal patterns and potential sources
- 2015
Medicine, Biology
The atherosclerotic process and its consequences are considered driven by an imbalance between pro- and ant-inflammatory actions, and one contributing factor is an altered regulation of these actions by the immune system.
MUW researcher of the month
- 2014
Medicine
Lebererkrankungen stellen die zweithäufigste Todesursache bei HIV-positiven Patienten dar. Verglichen mit der HCV (Hepatitis C Virus) Monoinfektion ist die HIV/HCV Koinfektion mit einer erhöhten…
27 References
Prognostic value of apoptosis markers in advanced heart failure patients.
- 2009
Medicine
AIMS
Apoptosis plays an important role in the progression of heart failure (HF). The purpose of this study was to assess whether the pro-apoptotic molecules apoptosis-stimulating fragment (FAS,…
The pro-apoptotic serum activity is an independent mortality predictor of patients with heart failure.
- 2004
Medicine
Serum Fas/FasL levels in dependence on clinical presentations of coronary disease and their relationship with risk factors.
- 2010
Medicine
The obtained results showed that apoptotic process is dysregulated in the patients with ischemic heart disease and interdependence between Fas and FasL and inflammatory and lipid markers as well as with cardiovascular risk factors was established.
Soluble Fas, a mediator of apoptosis, C-reactive protein, and coronary and extracoronary atherosclerosis. The Rotterdam Coronary Calcification Study.
- 2006
Medicine, Biology
Soluble Antiapoptotic Molecules and Immune Activation in Chronic Heart Failure and Unstable Angina Pectoris
- 2004
Medicine
The results demonstrated that mean levels of sFas and sIL2-R were significantly increased in patients affected by chronic heart failure and unstable angina and were not associated with changes in renal function or with serum levels of cTnI, indicating that the activation of Fas system is strictly associated with autoimmune–inflammatory reactions.
Soluble Fas is a marker of peripheral arterial occlusive disease in haemodialysis patients.
- 2002
Medicine
Increased plasma levels of sFas are associated with established PAOD and results suggest that sFAs may represent a novel and independent marker of atherosclerosis.
C-Reactive Protein Predicts Future Cardiovascular Events in Patients With Carotid Stenosis
- 2007
Medicine
Inflammation was associated with morphological and clinical progression of atherosclerotic disease and patients with elevated levels of hs-CRP exhibit an increased risk for adverse cardiovascular outcome attributable to clinical adverse events of progressive atherosclerosis.
Serum markers of apoptosis decrease with age and cancer stage
- 2009
Medicine
The shift toward less global apoptosis with increasing age in normal subjects is consistent with increased incidence of diseases whose pathophysiology involves apoptosis dysregulation.
Inflammation and Carotid Artery—Risk for Atherosclerosis Study (ICARAS)
- 2005
Medicine, Environmental Science
Evidence is supply for a close temporal correlation between inflammation and morphological features of rapidly progressive carotid atherosclerosis, which suggests that elevation or increase of the inflammatory biomarkers hs-CRP and SAA identifies the presence of active atherosclerotic disease.