The prognostic impact of anti-cancer immune response: a novel classification of cancer patients

  title={The prognostic impact of anti-cancer immune response: a novel classification of cancer patients},
  author={G. Bindea and B. Mlecnik and W. Fridman and J. Galon},
  journal={Seminars in Immunopathology},
  pages={335 - 340}
  • G. Bindea, B. Mlecnik, +1 author J. Galon
  • Published 2011
  • Biology, Medicine
  • Seminars in Immunopathology
  • Until now, the anatomic extent of tumor (TNM classification) has been, by far, the most important factor to predict the prognosis of colorectal cancer patients. However, in recent years, data collected from large cohorts of human cancers demonstrated that the immune contexture of the primary tumors is an essential prognostic factor for patients' disease-free and overall survival. Global analysis of tumor microenvironment showed that the nature, the functional orientation, the density, and the… CONTINUE READING

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