The prognostic impact of NF-κB p105, vimentin, E-cadherin and Par6 expression in epithelial and stromal compartment in non-small-cell lung cancer

@article{AlSaad2008ThePI,
  title={The prognostic impact of NF-κB p105, vimentin, E-cadherin and Par6 expression in epithelial and stromal compartment in non-small-cell lung cancer},
  author={Samer Al-Saad and Khalid I. Al-Shibli and Tom Donnem and Magnus Persson and Roy Martin Bremnes and Lill-Tove R. Busund},
  journal={British Journal of Cancer},
  year={2008},
  volume={99},
  pages={1476 - 1483}
}
Vimentin, nuclear factor-κB (NF-κB) p105, fascin, E-cadherin, TGF-β, Par6 and atypical PKC are molecular markers that play an important role in cell differentiation. Herein, we investigate their prognostic impact in primary non-small-cell carcinoma (NSCLC). Tumour tissue samples from 335 resected patients with stage I–IIIA were used. Tissue microarrays were constructed from duplicate cores of both neoplastic cells and stromal cells and were immunohistochemically evaluated. In univariate… CONTINUE READING
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