The prognosis of acute and subacute transverse myelopathy based on early signs and symptoms

  title={The prognosis of acute and subacute transverse myelopathy based on early signs and symptoms},
  author={Allan H. Ropper and DavidC. Poskanzer},
  journal={Annals of Neurology},
Fifty‐two patients with acute and subacute transverse myelopathy (TM) were evaluated at the Massachusetts General Hospital between 1955 and 1975 and followed for 1 to 23 years (average, 5). Nineteen had symptoms of a recent acute infectious illness, 3 had cancer, and 1 had undergone a recent operation. There were four types of initial symptom. Twenty‐four patients had paresthesias at the onset of the illness, 18 had pain, usually interscapular, 7 had leg weakness, and 3 had urine retention… 


The clinical features and outcome of idiopathic acute transverse myelopathy were reviewed for 21 children aged between seven months and 14 years, and the prognosis after acuteTransverse Myelopathy in childhood is a little better than that reported for adults.

Clinical course and long‐term prognosis of acute transverse myelopathy

The clinical characteristics and course of acute transverse myelopathy (ATM) was studied, and back‐pain and signs of spinal shock indicated a poor outcome.

Acute Transverse Myelitis in Children: Clinical Course and Prognostic Factors

The course of acute transverse myelitis in children proceeds through three stages, an initial phase, a plateau, and a recovery phase, each characterized by specific clinical features.

Acute transverse myelitis in childhood

Persisting disability was present in many children with acute transverse myelitis and age at onset below 3 years was associated with worse functional outcomes, while older age at time of diagnosis was associatedwith a better functional outcome.

Acute Transverse Myelopathy in Children

  • C. AdamsD. Armstrong
  • Medicine
    Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
  • 1990
Maximum motor recovery occurred at a mean of 6½ months but did not occur in one patient until 1½ years, and poor prognostic features were severity of weakness at the time of maximum deficit and a delayed onset of recovery.

Prognostic Parameters of Acute Transverse Myelitis in Children

Most children with acute transverse myelitis appear to have a good outcome, and clinical factors predicting good prognosis were cerebrospinal fluid pleocytosis, absence of tetraparesis, and prolonged time to nadir.

Idiopathic transverse myelitis: an experience in a tertiary care setup.

It did not behave very differently from what is reported in the international literature, with myelitis most commonly involving the dorsal spine, spanning over more than two spinal segments and showing complete or partial recovery in majority of cases with timely presentation for treatment.

Etiologic spectrum and functional outcome of the acute inflammatory myelitis

AIM is a heterogeneous syndrome from an etiological point of view and LETM patients had worse functional prognosis compared with PL after 3 and 6 months.

Prognostic predictors of acute transverse myelitis

Severity of weakness and denervation on EMG are most useful for predicting the outcome of ATM at 6 months although in early stage motor and somatosensory evoked potentials may be used instead of EMG.



Acute transverse myelopathy in adults. A follow-up study.

The only factor which correlated with prognosis was the observation that patients who retained tendon reflexes and posterior column function had a better recovery than those who exhibited spinal shock.


Despite its clinical recognition for several decades and its not infrequent occurrence, acute transverse myelopathy remains a poorly understood syndrome not only etiologically but also in terms of

Syndrome of the Anterior Spinal Artery

An analysis of the symptomatology in the light of present neuroanatomic knowledge and the differential diagnosis and relationship of prognosis to modern treatment justifies a review of the total problem.

Headache and Other Head Pain

The second edition of Harold Wolff's monograph on headache possesses many features not included in the original monograph, and contains an account of studies concerning the phenomena of vasoconstriction and the later painful vasodilation and lowered pain threshold which characterize the migraine attack.

Herpes zoster myelitis. Evidence for viral invasion of spinal cord.

Cowdry type A intranuclear inclusion bodies and structures in glial cells consistent with nucleocapsids of herpesvirus were observed in cervical spinal cord and the findings suggest that herpes zoster myelitis is mediated by direct viral invasion and cell lysis.

Case 26-1976

A 64-year-old woman was admitted to the hospital because of inability to walk when she experienced a "pulling" sensation in the right groin that persisted and was accompanied by urinary frequency and dysuria for several days.

Para-infectious encephalomyelitis and related syndromes; a critical review of the neurological complications of certain specific fevers.

In the encephalitis which follows measles, chickenpox, rubella, scarlet fever and mumps, there are so many similarities in the clinical picture, in the pathology and in the independence of the severity of the preceding illness that it is reasonable to look for a common mechanism.


Excerpt Neurologic reactions after antirabies vaccination are rare, but constitute the principal hazard in the use of this vaccine (1). These reactions occur in three main types: [1] peripheral neu...