The progesterone receptor regulates implantation, decidualization, and glandular development via a complex paracrine signaling network.

@article{Wetendorf2012ThePR,
  title={The progesterone receptor regulates implantation, decidualization, and glandular development via a complex paracrine signaling network.},
  author={Margeaux Wetendorf and Francesco J. Demayo},
  journal={Molecular and cellular endocrinology},
  year={2012},
  volume={357 1-2},
  pages={108-18}
}
Many women are affected by infertility and reproductive-associated disease such as endometriosis or endometrial cancer. Successful pregnancy is dependent on a healthy uterus that is fit to receive and support a fertilized embryo. The uterus is an endocrine organ, responsive to the presence of the ovarian steroid hormones, estrogen and progesterone, which activate transcription of target genes through the binding of their cognate receptors, the estrogen receptor and the progesterone receptor… CONTINUE READING
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