The profile of repeat-associated histone lysine methylation states in the mouse epigenome.

@article{Martens2005ThePO,
  title={The profile of repeat-associated histone lysine methylation states in the mouse epigenome.},
  author={Joost H. A. Martens and Roderick J O'sullivan and Ulrich Braunschweig and Susanne Opravil and Martin Radolf and Peter Steinlein and Thomas Jenuwein},
  journal={The EMBO journal},
  year={2005},
  volume={24 4},
  pages={800-12}
}
Histone lysine methylation has been shown to index silenced chromatin regions at, for example, pericentric heterochromatin or of the inactive X chromosome. Here, we examined the distribution of repressive histone lysine methylation states over the entire family of DNA repeats in the mouse genome. Using chromatin immunoprecipitation in a cluster analysis representing repetitive elements, our data demonstrate the selective enrichment of distinct H3-K9, H3-K27 and H4-K20 methylation marks across… CONTINUE READING
Highly Influential
This paper has highly influenced a number of papers. REVIEW HIGHLY INFLUENTIAL CITATIONS