The production of superoxide anion and nitric oxide by cultured murine leukocytes and the accumulation of TNF-alpha in the conditioned media is inhibited by taurine chloramine.

@article{Kim1996ThePO,
  title={The production of superoxide anion and nitric oxide by cultured murine leukocytes and the accumulation of TNF-alpha in the conditioned media is inhibited by taurine chloramine.},
  author={Christine Kim and Eunkyue Park and Michael R. Quinn and Georgia B. Schuller-Levis},
  journal={Immunopharmacology},
  year={1996},
  volume={34 2-3},
  pages={89-95}
}
Taurine chloramine (Tau-Cl) inhibits production of nitric oxide (NO) by activated peritoneal macrophages and attenuates accumulation of tumor necrosis factor-alpha (TNF-alpha) in the culture media, similar to that previously reported for activated RAW 264.7 cells. In addition, the effect of Tau-Cl and taurine on superoxide anion (O2-) production in murine peritoneal exudate polymorphonuclear leukocytes (PMN) was examined. Tau-Cl inhibited O2- production in a manner that was dose-dependent and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 27 extracted citations

The NADPH Oxidase Family and its Inhibitors

Archivum Immunologiae et Therapiae Experimentalis • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…