The production of reactive oxygen species and the mitochondrial membrane potential are modulated during onion oil-induced cell cycle arrest and apoptosis in A549 cells.

@article{Wu2006ThePO,
  title={The production of reactive oxygen species and the mitochondrial membrane potential are modulated during onion oil-induced cell cycle arrest and apoptosis in A549 cells.},
  author={Xin-jiang Wu and Thorsten Stahl and Ying Hu and Fekadu Kassie and Volker Mersch-Sundermann},
  journal={The Journal of nutrition},
  year={2006},
  volume={136 3},
  pages={608-13}
}
Protective effects of Allium vegetables against cancers have been shown extensively in experimental animals and epidemiologic studies. We investigated cell proliferation and the induction of apoptosis by onion oil extracted from Allium cepa, a widely consumed Allium vegetable, in human lung cancer A549 cells. GC/MS analysis suggested that propyl sulfides but not allyl sulfides are major sulfur-containing constituents of onion oil. Onion oil at 12.5 mg/L significantly induced apoptosis (13… CONTINUE READING

Similar Papers

Loading similar papers…