The production of myeloid blood cells and their regulation during health and disease.

@article{Broxmeyer1988ThePO,
  title={The production of myeloid blood cells and their regulation during health and disease.},
  author={Hal E. Broxmeyer and Douglas E. Williams},
  journal={Critical reviews in oncology/hematology},
  year={1988},
  volume={8 3},
  pages={173-226}
}
The regulation of myelopoiesis in vivo most likely entails a complex set of interactions between cell-derived biomolecules and their target cells: hematopoietic stem and progenitor cells and accessory cells. Stimulating and suppressing factors have been characterized through in vitro studies, and their mechanisms of action in vitro and in vivo have begun to be elucidated. Among those factors being studied are the hematopoietic colony-stimulating factors (CSF): interleukin-3 (multi-CSF… CONTINUE READING

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