The problem of the quiescent cancer cell.

Abstract

1. Antimetabolites and inhibitors of DNA topoisomerase II are relatively ineffective against quiescent cells. 2. Alkylating agents (carmustine, cisplatin) retain significant activity against Q-cells. 3. Of the various cytokinetic reasons why tumors may have slow growth rates (long cycle times, high cell loss factors, differentiation, Q-cells), modeling… (More)

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Cite this paper

@article{Jackson1989ThePO, title={The problem of the quiescent cancer cell.}, author={Robert C. Jackson}, journal={Advances in enzyme regulation}, year={1989}, volume={29}, pages={27-46} }