The problem of the quiescent cancer cell.


1. Antimetabolites and inhibitors of DNA topoisomerase II are relatively ineffective against quiescent cells. 2. Alkylating agents (carmustine, cisplatin) retain significant activity against Q-cells. 3. Of the various cytokinetic reasons why tumors may have slow growth rates (long cycle times, high cell loss factors, differentiation, Q-cells), modeling… (More)


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@article{Jackson1989ThePO, title={The problem of the quiescent cancer cell.}, author={Robert C. Jackson}, journal={Advances in enzyme regulation}, year={1989}, volume={29}, pages={27-46} }