The probability of abnormal preimplantation development can be predicted by a single static observation on pronuclear stage morphology.

@article{Tesak1999ThePO,
  title={The probability of abnormal preimplantation development can be predicted by a single static observation on pronuclear stage morphology.},
  author={J. Tesař{\'i}k and E. Greco},
  journal={Human reproduction},
  year={1999},
  volume={14 5},
  pages={
          1318-23
        }
}
  • J. Tesařík, E. Greco
  • Published 1999
  • Medicine, Biology
  • Human reproduction
  • This retrospective study was undertaken to determine whether further developmental progression of two-pronucleated (2PN) zygotes can be predicted by a single, non-invasive examination of pronuclei, with the use of criteria based on the number and distribution of nucleolar precursor bodies in each pronucleus. The normal range of pronuclear variability was defined by analysis of zygotes giving rise to embryos transferred in 100%-implantation cycles (pattern 0). Morphological patterns differing… CONTINUE READING

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