The proangiogenic factor ephrin-A1 is up-regulated in radioresistant murine tumor by irradiation.

@article{Nojiri2009ThePF,
  title={The proangiogenic factor ephrin-A1 is up-regulated in radioresistant murine tumor by irradiation.},
  author={Kazunori Nojiri and Mayumi Iwakawa and Yasushi Ichikawa and Kaori Imadome and Minako Sakai and Miyako Nakawatari and Ken-ichi Ishikawa and Atsuko Ishikawa and Shinji Togo and Hirohiko Tsujii and Hiroshi Shimada and Takashi Imai},
  journal={Experimental biology and medicine},
  year={2009},
  volume={234 1},
  pages={112-22}
}
While the pre-treatment status of cancer is generally correlated with outcome, little is known about microenvironmental change caused by anti-cancer treatment and how it may affect outcome. For example, treatment may lead to induction of gene expression that promotes resistance to therapy. In the present study, we attempted to find a gene that was both induced by irradiation and associated with radioresistance in tumors. Using single-color oligo-microarrays, we analyzed the gene expression… CONTINUE READING
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