The pro- and anti-inflammatory properties of human antigen-presenting cells expressing the high affinity receptor for IgE (Fc epsilon RI).


Almost 20 years after the first description of IgE on the surface of epidermal Langerhans cells (LC) and the subsequent characterization of the trimeric Fc epsilon RI on human antigen-presenting cells (APC), we have gained profound insights into the receptor responsible for this binding. Fc epsilon RI may act as a pro-inflammatory structure on some APC such… (More)


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