The prime role of HDL to transport lutein into the retina: evidence from HDL-deficient WHAM chicks having a mutant ABCA1 transporter.

@article{Connor2007ThePR,
  title={The prime role of HDL to transport lutein into the retina: evidence from HDL-deficient WHAM chicks having a mutant ABCA1 transporter.},
  author={William E. Connor and P. Barton Duell and R. M. Kean and Yingming Wang},
  journal={Investigative ophthalmology & visual science},
  year={2007},
  volume={48 9},
  pages={
          4226-31
        }
}
PURPOSE Lutein and zeaxanthin are largely transported in plasma by high-density lipoprotein (HDL). The Wisconsin hypoalpha mutant (WHAM) chicken has a recessive sex-linked mutation in the ABCA1 transporter gene that results in a severe deficiency of HDL. In this study, the transport and tissue distribution of lutein and zeaxanthin were examined in newly hatched and 28-day-old WHAM chicks compared with control chicks. METHODS One-day-old WHAM and control chicks were randomized to be fed a high… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 49 CITATIONS

Developmentally Regulated Production of meso-Zeaxanthin in Chicken Retinal Pigment Epithelium/Choroid and Retina

  • Investigative ophthalmology & visual science
  • 2016
VIEW 4 EXCERPTS
CITES METHODS & BACKGROUND
HIGHLY INFLUENCED

Apolipoprotein E genotype is associated with macular pigment optical density.

  • Investigative ophthalmology & visual science
  • 2010
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

References

Publications referenced by this paper.
SHOWING 1-10 OF 37 REFERENCES

The macular xanthophylls.

  • Survey of ophthalmology
  • 2005
VIEW 1 EXCERPT