The primary structure of the cytotoxin restrictocin.

  title={The primary structure of the cytotoxin restrictocin.},
  author={Carlos L{\'o}pez-Ot{\'i}n and Domingo Barber and Jos{\'e} Luis Fern{\'a}ndez-Luna and Fernando Soriano and Enrique B Mendez},
  journal={European journal of biochemistry},
  volume={143 3},
The complete amino acid sequence of the single polypeptide chain of cytotoxin restrictocin has been determined. Its structure was established by automated Edman degradation of the intact molecule reduced and [14C]carboxymethylated and of fragments obtained by chemical cleavage of the protein with cyanogen bromide and BNPS-skatole and by enzymatic cleavage of the polypeptide chain with trypsin. The molecule consists of 149 amino acid residues with a calculated relative molecular mass of 16836… CONTINUE READING