The prevalence and clinical significance of C1q-binding donor-specific anti-HLA antibodies early and late after kidney transplantation.

@article{CalpInal2016ThePA,
  title={The prevalence and clinical significance of C1q-binding donor-specific anti-HLA antibodies early and late after kidney transplantation.},
  author={Sumeyye Calp-Inal and Maria Ajaimy and Michal Melamed and Christina Savchik and Peter T. Masiakos and Adriana Ioana Colovai and Enver Akalin},
  journal={Kidney international},
  year={2016},
  volume={89 1},
  pages={
          209-16
        }
}
We aimed to determine the prevalence and clinical significance of complement-binding donor-specific antibodies (DSA) detected up to 30 years after kidney transplantation. Group 1 patients included 284 consecutive DSA negative patients who underwent kidney transplantation after 1 May 2009. Group 2 included 405 patients transplanted before this date and followed at our center with functioning allografts. DSA were tested using Luminex Single Antigen and the C1q assay. In Group 1 patients, who were… CONTINUE READING
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