• DOI:10.1007/s13277-015-4601-x
Corpus ID: 16036612

The prevalence and clinical profiles of FLT3-ITD, FLT3-TKD, NPM1, C-KIT, DNMT3A, and CEBPA mutations in a cohort of patients with de novo acute myeloid leukemia from southwest China

@article{Gou2015ThePA,
  title={The prevalence and clinical profiles of FLT3-ITD, FLT3-TKD, NPM1, C-KIT, DNMT3A, and CEBPA mutations in a cohort of patients with de novo acute myeloid leukemia from southwest China},
  author={Haimei Gou and J. Zhou and Yuanxin Ye and X. Hu and Mengqiao Shang and J. Zhang and Zhenzhen Zhao and W. Peng and Yanhong Zhou and Y. Zhou and X. Song and X. Lu and B. Ying},
  journal={Tumor Biology},
  year={2015},
  volume={37},
  pages={7357-7370}
}

Haimei Gou, J. Zhou, +10 authors B. Ying

Published 2015

Medicine

Tumor Biology

While a substantial amount of data on gene mutations related to acute myeloid leukemia (AML) prognosis from western and other populations have been reported, these studies largely describe one or two genes. Additionally, in southwest China, only insufficient data exist regarding FLT3-ITD, FLT3-TKD, NPM1, C-KIT, DNMT3A, and CEBPA mutations have been widely used in clinical settings. Therefore, a comprehensive study about these mutations of clinical importance in the prognosis of AML in western… CONTINUE READING

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