The prevalence, severity, and impact of opioid-induced bowel dysfunction: results of a US and European Patient Survey (PROBE 1).

@article{Bell2009ThePS,
  title={The prevalence, severity, and impact of opioid-induced bowel dysfunction: results of a US and European Patient Survey (PROBE 1).},
  author={Timothy J Bell and Sunil J. Panchal and Christine Miaskowski and Susan C. Bolge and Tsveta F Milanova and Russell Williamson},
  journal={Pain medicine},
  year={2009},
  volume={10 1},
  pages={35-42}
}
OBJECTIVE This multinational, Internet-based survey was designed to assess the prevalence, frequency, severity, and impact of opioid-induced bowel dysfunction (OBD) in patients receiving opioid therapy for chronic pain and taking laxatives. DESIGN In total, 322 patients taking daily oral opioids and laxatives completed the 45-item questionnaire. At the time of the survey, 45% of patients reported <3 bowel movements per week. The most prevalent opioid-induced side effects were constipation (81… CONTINUE READING
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