The pressure-volume diagram of the thorax and lung.

  title={The pressure-volume diagram of the thorax and lung.},
  author={Hermann Rahn and Arthur B. Otis and Wallace O. Fenn},
  journal={Federation proceedings},
  volume={5 1 Pt 2},
It is remarkable that physiologists have paid so little attention in the past to the mechanics of breathing that no adequate data are now on record concerning the pressure-volume characteristics of the chest and lungs in normal men. [] Key Method Measurements were made with a recording mercury manometer connected to a one hole rubber stopper cut to fit one nostril. The other nostril was held closed while the subject expired or inspired with maximum force.

The Effect of Intermittent Positive Pressure Breathing on the Lung Compliance and Intrapulmonary Mixing of Gases

It is suggested that positive pressure breathing might result in over-distension of some areas of lung and under-ventilation of others, and the compliance measured under such circumstances would be lower than that of the same lung when naturally and evenly inflated by the action of the respiratory muscles.

Pressure—volume relationships in the chest before and after death

Findings in the rabbit and the cat before and up to 18 hr after death are discussed, and immediate mortal changes are shown to be mainly an exaggeration of mechanical characteristics already present in the living chest.

Pressure-volume curve: methods and meaning.

There is considerable experimental evidence that both the opening-collapse phenomena and the excessive lung stretch may cause damage to the lungs, so tools allowing an individual titration of ventilatory settings taking into account the constraints of the respiratory system seem highly desirable.

The pressure-volume relationship of a forced breathing cycle.

It is expected that in respiratory manoeuvres involving maximum effort and lasting less than three seconds, the pressures should be greater than those attained under the isometric conditions of RAHN et af.

Mechanics of respiration.

  • W. O. Fenn
  • Medicine
    The American journal of medicine
  • 1951

The elastic pressure‐volume curves of the lungs and thorax of the living rabbit *

When Bayliss & Robertson's published tracings were analysed into their component curves, of intratracheal pressure and pump displacement against time, the pressure curve was found to be distorted from sine wave form in qualitatively the same way as the curves described above.

A century of the mechanics of breathing.

  • P. Macklem
  • Physics
    American journal of respiratory and critical care medicine
  • 2004
This review is not comprehensive, but focuses on the role of models and technology in the development of new knowledge in the field and on discoveries related to surface tension.

Mechanics of airflow in health and in emphysema.

  • H. Dayman
  • Medicine
    The Journal of clinical investigation
  • 1951
To determine whether such a mechanism exists, the method of Neergaard and Wirz was employed, which, under suitable conditions, provides a continuous record of pleural pressure and rate of airflow, which suggested the presence of expiratory obstruction which is aggravated by increasing the expulsive force.



Am. J. Med. Sci

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  • 1921

Pfliiger's Arch

  • U. S. Naval Med. Bull
  • 1921

Lung volumes of IO subjects in the supine position at diferent relaxation pressures SUBJECT

  • Lung volumes of IO subjects in the supine position at diferent relaxation pressures SUBJECT

Arch f. exper. Path. u. Pharmakol

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Todd's cyclopaedia of anatomy and physiology

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Pfliiger's Arch

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Arch f. exper. Path. Suppl

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Pfliiger's Arch

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