The present status of the ‘carrier hypothesis’ for chemosensory recognition of genetic individuality

Abstract

The hypothesis that soluble MHC Class I molecules could act as the vector which transports MHC‐specific odours from the blood into the urine was put forward some ten years ago (Singh, Brown Roser, 1987). Here, I summarise new evidence in favour of the hypothesis. ‘We propose that the ability of MHC Class I molecules to associate in a selective way with other small molecules could also be the mechanism by which a unique mixture of volatile, endogenous metabolites is transported by [soluble] class I MHC glycoproteins from the blood into the urine’ (Singh, Brown Roser, 1987).

DOI: 10.1023/A:1026475118901

Cite this paper

@article{Singh1998ThePS, title={The present status of the ‘carrier hypothesis’ for chemosensory recognition of genetic individuality}, author={Prim B . Singh}, journal={Genetica}, year={1998}, volume={104}, pages={231-233} }