The presence within single K-562 cells of erythropoietic and granulopoietic differentiation markers.

@article{Marie1981ThePW,
  title={The presence within single K-562 cells of erythropoietic and granulopoietic differentiation markers.},
  author={J P Marie and C. A. Izaguirre and Curt I. Civin and Joseph Mirro and E A Mcculloch},
  journal={Blood},
  year={1981},
  volume={58 4},
  pages={708-11}
}
The continuous cell line K-562, derived from a patient with CML in blast crisis, was examined for markers of granulopoietic (My-1) and erythropoietic (spectrin) differentiation, using specific antibodies detected by indirect immunofluorescence. Both markers were seen, and in 10%--30% of cells, both were present in the same cells. In contrast, the continuous… CONTINUE READING