The presence of urinary nitrites is a significant predictor of pediatric urinary tract infection susceptibility to first- and third-generation cephalosporins.

@article{Weisz2010ThePO,
  title={The presence of urinary nitrites is a significant predictor of pediatric urinary tract infection susceptibility to first- and third-generation cephalosporins.},
  author={Dany E. Weisz and Jamie A. Seabrook and Rodrick K Lim},
  journal={The Journal of emergency medicine},
  year={2010},
  volume={39 1},
  pages={6-12}
}
BACKGROUND Previous studies in adults have refuted the use of nitrites as a predictor of bacterial resistance to both trimethoprim-sulfamethoxazole and cephalosporins. Some centers now consider first-line outpatient therapy with an oral third-generation cephalosporin appropriate for young children. OBJECTIVE The objective of this study was to determine if nitrite-negative pediatric urinary tract infections (UTIs) were more likely than nitrite-positive UTIs to be resistant to cephalosporins… CONTINUE READING

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