The presence of genotoxic and bioactive components in indigo dyed fabrics--a possible health risk?

@article{Rannug1992ThePO,
  title={The presence of genotoxic and bioactive components in indigo dyed fabrics--a possible health risk?},
  author={Ulf Rannug and H Bramstedt and Ulf Nilsson},
  journal={Mutation research},
  year={1992},
  volume={282 3},
  pages={219-25}
}
Extracts of pure cotton and jeans fabrics were tested for mutagenicity in Salmonella typhimurium strains TA98 and TA100. The vat dye indigo, technical grade as well as 98% and greater than 99.5% pure, was also tested for mutagenicity. Synthetic indigo, indirubin and isatin were tested for TCDD receptor affinity in competition experiments in vitro. The mutagenicity of the extracts was associated with the cotton denim and nondyed cotton gave only marginal effects. The mutagenicity of the indigo… CONTINUE READING

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