The presence of HBV mRNA in the fertilized in vitro embryo of HBV patients confirms vertical transmission of HBV via the ovum

@article{Ye2012ThePO,
  title={The presence of HBV mRNA in the fertilized in vitro embryo of HBV patients confirms vertical transmission of HBV via the ovum},
  author={Feng Ye and Y. Jin and Ying Kong and J. Shi and Hongtao Qiu and X. Zhang and S. L. Zhang and S. M. Lin},
  journal={Epidemiology and Infection},
  year={2012},
  volume={141},
  pages={926 - 930}
}
  • F. Ye, Y. Jin, +5 authors S. Lin
  • Published 9 August 2012
  • Biology, Medicine
  • Epidemiology and Infection
SUMMARY This study aimed to confirm that vertical transmission of hepatitis B virus (HBV) can occur via the infected ovum. Specimens studied were obtained from discarded test-tube embryos from mothers with chronic HBV infection who had received in vitro fertilization treatment. Single-cell reverse transcriptase–polymerase chain reaction was used to detect HBV mRNA in the embryos. HBV mRNA was detected in the cleavage embryos of patients with chronic HBV infection, with a detection rate of 13·2… 
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Chronic hepatitis B virus infection in women is not associated with IVF/ICSI outcomes
TLDR
The results indicated that women with chronic HBV infection is not associated with outcomes of IVF/ICSI treatments, and there was no significant differences in implantation rates and live birth rates between seropositive women group and matched control.
Prevention of Perinatal Hepatitis B Virus Transmission.
TLDR
Screening pregnant women for HBV infection, providing infant postexposure prophylaxis, and maternal treatment with antiviral medications are strategies for reducing MTCT transmission rates and the global burden of new chronic HBV infections.
Detection of hepatitis B virus infection: A systematic review.
TLDR
Serological and molecular assays are predominant and reliable methods for HBV detection and Automated systems are highly sensitive and quantify HBV DNA and serological markers for monitoring.
Hepatitis B virus in the Arab world: where do we stand?
  • G. I. Gasim
  • Medicine
    Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology
  • 2013
Human Oocytes Express Both ACE2 and BSG Genes and Corresponding Proteins: Is SARS-CoV-2 Infection Possible?
TLDR
The human oocyte transcriptome and proteome obtained in previous studies were reviewed and found that human oocytes from the in vitro fertilization program expressed both the ACE2 and BSG genes and the corresponding ACE2and BSG proteins, which means thathuman oocytes possess the molecular ‘machinery’ to facilitate SARS-CoV-2 entrance and infection.
Issues des transferts cumulés d’embryons frais et congelés en fécondation in vitro chez les femmes infectées par le virus de l’hépatite B

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