The presence in experimental animals of a colon specific Mr 40,000 protein(s) with relevance to ulcerative colitis.

@article{Biancone1991ThePI,
  title={The presence in experimental animals of a colon specific Mr 40,000 protein(s) with relevance to ulcerative colitis.},
  author={Livia Biancone and Lisa Wise and Kiron Moy Das},
  journal={Gut},
  year={1991},
  volume={32 5},
  pages={504-8}
}
In patients with ulcerative colitis a colon tissue bound IgG and serum antibodies against an Mr 40,000 colonic protein(s) has been identified. Using an anti-Mr 40,000 protein monoclonal antibody, 7E12H12, by an immunocytochemical method, the protein was localised in human tissue exclusively to colonic epithelial cells. In this study the presence of the Mr… CONTINUE READING