The presence and impact of biofilm-producing staphylococci in atopic dermatitis.

  title={The presence and impact of biofilm-producing staphylococci in atopic dermatitis.},
  author={Herbert B. Allen and Nachiket D. Vaze and Catherine H. Choi and Tesfu Hailu and Brittain H Tulbert and Carrie Ann R Cusack and S G Joshi},
  journal={JAMA dermatology},
  volume={150 3},
IMPORTANCE Atopic dermatitis (AD) is thought to be a double-hit phenomenon with an unknown environmental component and a genetic abnormality likely centered on the filaggrin gene. Biologically, the presence of Staphylococcus aureus in AD was reported more than 2 decades ago, but the relationship to AD has been elusive. OBJECTIVE To explore the bacteria that produce the biofilms in the lesions of AD and the response of the innate immune system to these biofilm occlusions of the sweat ducts by… CONTINUE READING
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The earliest immunologic finding in atopic dermatitis: periductal Toll-like receptor 2 expression in response to ductal occlusion by Staphylococcus epidermidis biofilm

  • C Choi, T Hailu, CA Cusack, HB Allen, S Lodha, T. Hailu
  • J Am Acad Dermatol
  • 2012

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