The presence, role and clinical use of spermatozoal RNAs.

  title={The presence, role and clinical use of spermatozoal RNAs.},
  author={Meritxell Jodar and S Selvaraju and Edward D Sendler and Michael Peter Diamond and Stephen A. Krawetz},
  journal={Human reproduction update},
  volume={19 6},
BACKGROUND Spermatozoa are highly differentiated, transcriptionally inert cells characterized by a compact nucleus with minimal cytoplasm. Nevertheless they contain a suite of unique RNAs that are delivered to oocyte upon fertilization. They are likely integrated as part of many different processes including genome recognition, consolidation-confrontation, early embryonic development and epigenetic transgenerational inherence. Spermatozoal RNAs also provide a window into the developmental… CONTINUE READING


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