The preparation of a lipidic endotoxin affects its biological activities.

@article{Okemoto2008ThePO,
  title={The preparation of a lipidic endotoxin affects its biological activities.},
  author={Kazuo Okemoto and Kentaro Hanada and Masahiro Nishijima and Kiyoshi Kawasaki},
  journal={Biological & pharmaceutical bulletin},
  year={2008},
  volume={31 10},
  pages={1952-4}
}
Bacterial membrane constituents, such as Ornithine-containing lipid (OL) and the lipid A portion of lipopolysaccharide, trigger various immune responses through recognition by Toll-like receptor (TLR) 4. Usually, these lipids are dissolved in a small amount of aqueous or organic solvent before being added to the culture medium for examination of their… CONTINUE READING