The prelimbic cortex contributes to the down-regulation of attention toward redundant cues.

@article{Sharpe2014ThePC,
  title={The prelimbic cortex contributes to the down-regulation of attention toward redundant cues.},
  author={Melissa J Sharpe and Simon Killcross},
  journal={Cerebral cortex},
  year={2014},
  volume={24 4},
  pages={1066-74}
}
Previous research suggests disruption of activity in the prelimbic (PL) cortex produces deficits in tasks requiring preferential attention toward cues that are good predictors of an event. By manipulating cue predictive power, we clarify this role using Pavlovian conditioning. Experiment 1a showed pretraining excitotoxic lesions of the PL cortex disrupted the ability of animals to distribute attention across stimuli conditioned in compound. Experiment 1b demonstrated that these lesions did not… CONTINUE READING
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