The pregnancy-specific glycoprotein family of the immunoglobulin superfamily: identification of new members and estimation of family size.
@article{Khan1992ThePG, title={The pregnancy-specific glycoprotein family of the immunoglobulin superfamily: identification of new members and estimation of family size.}, author={W. Khan and S. Teglund and K. Bremer and S. Hammarstr{\"o}m}, journal={Genomics}, year={1992}, volume={12 4}, pages={ 780-7 } }
The members of the carcinoembryonic antigen (CEA)/pregnancy-specific glycoprotein (PSG) gene family have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. We have estimated the size of the PSG subfamily by identification of N-domain exons from isolated genomic clones and from total genomic DNA through PCR amplification and DNA sequence determination. The PSG subfamily contains at least 11 different genes. For 7 of these, two DNA sequences differing… CONTINUE READING
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