The prefrontal cortex and flexible behavior.

@article{Barbas2007ThePC,
  title={The prefrontal cortex and flexible behavior.},
  author={Helen Barbas and Basilis Zikopoulos},
  journal={The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry},
  year={2007},
  volume={13 5},
  pages={532-45}
}
The prefrontal cortex in primates guides behavior by selecting relevant stimuli for the task at hand, mediated through excitatory bidirectional pathways with structures associated with sensory processing, memory, and emotions. The prefrontal cortex also has a key role in suppressing irrelevant stimuli through a mechanism that is not well understood. Recent findings indicate that prefrontal pathways interface with laminar-specific neurochemical classes of inhibitory neurons in sensory cortices… CONTINUE READING
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