The prefrontal cortex: response selection or maintenance within working memory?
@article{Rowe2000ThePC, title={The prefrontal cortex: response selection or maintenance within working memory?}, author={J. Rowe and I. Toni and O. Josephs and R. Frackowiak and R. Passingham}, journal={Science}, year={2000}, volume={288 5471}, pages={ 1656-60 } }
It is controversial whether the dorsolateral prefrontal cortex is involved in the maintenance of items in working memory or in the selection of responses. We used event-related functional magnetic resonance imaging to study the performance of a spatial working memory task by humans. We distinguished the maintenance of spatial items from the selection of an item from memory to guide a response. Selection, but not maintenance, was associated with activation of prefrontal area 46 of the dorsal… Expand
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- 346
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- 43
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- 2003
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- 2002
- 461
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References
SHOWING 1-10 OF 60 REFERENCES
Maintenance versus Manipulation of Information Held in Working Memory: An Event-Related fMRI Study
- Psychology, Medicine
- Brain and Cognition
- 1999
- 723
- PDF
Temporal dynamics of brain activation during a working memory task
- Psychology, Medicine
- Nature
- 1997
- 1,765
- PDF
Human Prefrontal Cortex Is Not Specific for Working Memory: A Functional MRI Study
- Psychology, Medicine
- NeuroImage
- 1998
- 135
- PDF
Association of Storage and Processing Functions in the Dorsolateral Prefrontal Cortex of the Nonhuman Primate
- Psychology, Medicine
- The Journal of Neuroscience
- 1999
- 154
- PDF
Functional organization of spatial and nonspatial working memory processing within the human lateral frontal cortex.
- Psychology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 1998
- 344
- PDF
Dissociation of mnemonic and perceptual processes during spatial and nonspatial working memory using fMRI
- Psychology, Medicine
- Human brain mapping
- 1998
- 202
- PDF
Redefining the functional organization of working memory processes within human lateral prefrontal cortex
- Psychology, Medicine
- The European journal of neuroscience
- 1999
- 289
- PDF
Evidence for a two-stage model of spatial working memory processing within the lateral frontal cortex: a positron emission tomography study.
- Computer Science, Medicine
- Cerebral cortex
- 1996
- 731
- PDF
Transient and sustained activity in a distributed neural system for human working memory
- Psychology, Medicine
- Nature
- 1997
- 905
- PDF
Prefrontal neuronal activity in rhesus monkeys performing a delayed anti-saccade task
- Psychology, Medicine
- Nature
- 1993
- 640
- PDF