The predominant genotypes of hepatitis B virus in Thailand.

  title={The predominant genotypes of hepatitis B virus in Thailand.},
  author={Apiradee Theamboonlers and Pojchanad Jantaradsamee and N Kaew-in and Pisit Tangkijvanich and Petra Hirsch and Yong Poovorawan},
  journal={Annals of tropical medicine and parasitology},
  volume={93 7},
In Thailand, chronic liver disease (CLD) as a consequence of infection with hepatitis B virus (HBV) constitutes a public-health burden. Control and treatment are complicated by the virus exhibiting an unusually high mutation rate, with some genotypes apparently causing more severe disease than others. Restriction-fragment-length-polymorphism (RFLP) analysis of the pre-S region of the viral genome, amplified by PCR, was used to determine which genotypes were most prevalent among Thai patients… CONTINUE READING