The prediction of malignant cerebral infarction by molecular brain barrier disruption markers.

@article{Serena2005ThePO,
  title={The prediction of malignant cerebral infarction by molecular brain barrier disruption markers.},
  author={Joaqu{\'i}n Serena and M Victoria Blanco and Mar Castellanos and Yolanda Silva and Jos{\'e} Vivancos and Mar{\'i}a {\'A}ngeles Moro and Rogelio Leira and Ignacio Lizasoain and J. Vx00E1zquez Castillo and Antoni Davalos},
  journal={Stroke},
  year={2005},
  volume={36 9},
  pages={1921-6}
}
BACKGROUND AND PURPOSE Space-occupying brain edema is a life-threatening complication in patients with large hemispheric stroke. The aim of the study was to determine whether molecular markers of endothelial damage may help to predict secondary brain edema and, secondly, to identify patients who could benefit from aggressive therapies such as decompressive hemicraniectomy or hypothermia. METHODS We studied 40 consecutive patients with malignant middle cerebral artery (MCA) infarction and 35… CONTINUE READING

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