The predicted DBL oncogene product defines a distinct class of transforming proteins.

@article{Eva1988ThePD,
  title={The predicted DBL oncogene product defines a distinct class of transforming proteins.},
  author={Alessandra Eva and Giancarlo Vecchio and C. Dimps Rao and Steven R. Tronick and Stuart A. Aaronson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1988},
  volume={85 7},
  pages={2061-5}
}
The DBL transforming gene was originally identified by transfection of NIH 3T3 cells with DNA from a human B-cell lymphoma. This gene was found to have arisen as a result of recombination of the 3' portion of the DBL protooncogene coding sequences with an unrelated segment of human DNA. It encodes a cytoplasmic protein that is equally distributed between cytosol and crude membrane fractions. To further characterize this transforming gene, a biologically active cDNA clone of the DBL transforming… CONTINUE READING
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