The precursor of mouse β-globin messenger RNA contains two intervening RNA sequences
@article{Kinniburgh1978ThePO, title={The precursor of mouse $\beta$-globin messenger RNA contains two intervening RNA sequences}, author={Alan J. Kinniburgh and Janet E. Mertz and Jeff Ross}, journal={Cell}, year={1978}, volume={14}, pages={681-693} }
73 Citations
The sequence of the chromosomal mouse β-globin major gene: Homologies in capping, splicing and poly(A) sites
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Inserts within the mRNA sequence on the 15 S globin mRNA precursor from chicken.
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Splicing patterns of nuclear precursors to the mRNA for adenovirus 2 DNA binding protein
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The size of the transcriptional units of the avian globin genes defined at the pre-messenger RNA level.
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The intervening sequence of a mouse beta-globin gene is transcribed within the 15S beta-globin mRNA precursor.
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- 1978
Using the electron microscope to visualize hybrid structures formed between this gene and the purified 15S beta-globin mRNA precursor, it is shown that the intervening sequence is present within the larger precursor molecule.
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It is concluded that nucleated erythroid cells obtained from the spleens of anemic mice have a 15S RNA which contains globin messenger RNA sequences and is a good candidate for a globin mRNA precursor.
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